For quest-only bosses, see quest boss.Many of the "Special" type infected types also have a boss form, which looks like a "Supercharged" version except without the floating skulls. These bosses have deadly attacks and an extremely large amount of HP.

Each boss will only drop good loot (including experience and reputation) once a week. If you kill them more often, you will get poor loot.

Infected Health Location Ability Secondary Ability
Sacramento Suburbs Summons exploders and basic infected to attack players. Throws a gas canister that explodes and deals fire damage in a 3m radius.
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The green circle around the Exploder are the toxic elements it attacks with.

Walker River Counter attacks with fire and toxic elements.
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Boss spawning mini crawlers.

Downtown Santa Rosa Summons mini crawlers to protect itself. Inflicts a painful bite.
Bodega Bay Vomits and does elemental damage (toxic, fire or ice) in a 5m radius.
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The Avengers get so angry that they kill any infecteds in their way as well as actual players.

Sunset Mall Becomes angrier the more damage it takes.
Highway 99, South Fallon Exit 6B Summons minions and protects them from damage.
  • The vomiter frequently spawns on the beach south of where you meet Karen Jade
  • The avenger spawns in the hedge maze in the Sunset Mall
  • The exploder spawns at a gas station at the far left of Walker River
  • The protector spawns just in front of the quarantine sp in the room
  • The other bosses may be found anywhere on the map outside secret passages